DBNL Antikörper (AA 201-300) (AbBy Fluor® 594)

Produktnummer ABIN6979411

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DBNL in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für DBNL Antikörper (AA 201-300) (AbBy Fluor® 594) (ABIN6979411)

Target: DBNL (Drebrin-Like (DBNL))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DBNL Antikörper ist konjugiert mit AbBy Fluor® 594

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-DBNL Antikörper (AbBy Fluor® 594)

Bindungsspezifität: AA 201-300

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HIP55

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DBNL

Target: DBNL (Drebrin-Like (DBNL))

Andere Bezeichnung: HIP55

Hintergrund:

Synonyms: ABP1, Actin-binding protein 1, Cervical mucin associated protein, Cervical mucin-associated protein, Cervical SH3P7, CMAP, Dbnl, DBNL_HUMAN, Drebrin F, drebrin like, Drebrin like protein, Drebrin-F, Drebrin-like protein, HIP 55, HIP-55, HPK1 interacting protein of 55 kDa, HPK1-interacting protein of 55 kDa, SH3 domain containing protein 7, SH3 domain-containing protein 7, SH3P7, Src Homology 3 Domain Containing Protein, src homology 3 domain containing protein HIP

Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

Gen-ID: 28988

UniProt: Q9UJU6

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization