GPC1 Antikörper (AA 251-350) (AbBy Fluor® 555)

Produktnummer ABIN6978749

This anti-GPC1 antibody (ABIN6978749) is a Rabbit Polyclonal antibody detecting GPC1 in IF (cc), IF (p). Suitable for Rat.

Kurzübersicht für GPC1 Antikörper (AA 251-350) (AbBy Fluor® 555) (ABIN6978749)

Target: GPC1 (Glypican 1 (GPC1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPC1 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-GPC1 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Ratte

Homologie: Mouse,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Glypican 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu GPC1

Target: GPC1 (Glypican 1 (GPC1))

Andere Bezeichnung: Glypican 1

Hintergrund:

Synonyms: FLJ38078, glypican, glypican1, GPC 1, Glypican-1, GPC1, Glypican proteoglycan 1, Gpc1, GPC1_HUMAN, Secreted glypican-1.

Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparin sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Gen-ID: 14733

UniProt: Q9QZF2

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation