CBX4 Antikörper (AA 401-500) (AbBy Fluor® 350)
Kurzübersicht für CBX4 Antikörper (AA 401-500) (AbBy Fluor® 350) (ABIN6976674)
Target
Alle CBX4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 401-500
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Dog,Sheep,Pig,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human CBX4
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Isotyp
- IgG
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anti-Chromobox Homolog 4 (CBX4) (AA 397-514) antibody
CBX4 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 6C5G3 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-160) antibodyCBX4 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 80-110), (N-Term) antibodyCBX4 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2931 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-560) antibodyCBX4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 401-500) antibodyCBX4 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 410-437), (C-Term) antibodyCBX4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB2934 unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 1-290) antibodyCBX4 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (N-Term) antibodyCBX4 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 53-102) antibodyCBX4 Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Chromobox Homolog 4 (CBX4) (AA 150-200) antibodyCBX4 Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- CBX4 (Chromobox Homolog 4 (CBX4))
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Andere Bezeichnung
- CBX4
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Hintergrund
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Synonyms: PC2, NBP16, E3 SUMO-protein ligase CBX4, Chromobox protein homolog 4, Polycomb 2 homolog, hPc2, CBX4
Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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Gen-ID
- 8535
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UniProt
- O00257
Target
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