TRIM37 Antikörper (C-Term)

Produktnummer ABIN6972886

Produktdetails anti-TRIM37 Antikörper

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM37 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: TRIM37 (Tripartite Motif Containing 37) is an E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:686, PubMed:972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:042). Has anti-HIV activity (PubMed:724). TRIM37 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human TRIM37.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Andere Bezeichnung: TRIM37 (TRIM37 Produkte)

Molekulargewicht: 120 kDa

NCBI Accession: NP_056109