SIP1 Antikörper (N-Term)

Produktnummer ABIN6972709

Produktdetails anti-SIP1 Antikörper

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: SIP1 (Smad-interacting protein 1, aka ZEB2, Zinc finger E-box-binding homeobox 2) is a sequence-specific DNA binding protein and transcriptional repressor that is involved in normal embryonic development of neural structures and the neural crest. SIP1 belongs to the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins and contains a SMAD-binding domain, a homeodomain and two clusters of zinc fingers on the N- and C-termini. SIP1 interacts directly with activated forms of SMAD1, SMAD2 and SMAD3, as well as CBX4 and CTBP1. Mutations in the SIP1 gene cause a form of Hirschsprung disease (HSCR). SIP1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This SIP1 antibody was raised against a peptide from the N-terminus of human SIP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu SIP1

Target: SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))

Andere Bezeichnung: SIP1 (GEMIN2 Produkte)

Synonyme: SIP1 antikoerper, SIP1-delta antikoerper, 1700012N19Rik antikoerper, Sip1 antikoerper, sip1 antikoerper, sip1-delta antikoerper, wu:fc52a05 antikoerper, zgc:110274 antikoerper, gem nuclear organelle associated protein 2 antikoerper, gem (nuclear organelle) associated protein 2 antikoerper, gem nuclear organelle associated protein 2 S homeolog antikoerper, GEMIN2 antikoerper, Gemin2 antikoerper, gemin2.S antikoerper, gemin2 antikoerper

Molekulargewicht: 180 kDa

NCBI Accession: NP_055610

Pathways: Ribonucleoprotein Complex Subunit Organization, Tube Formation