PRMT6 Antikörper (N-Term)

Produktnummer ABIN6972556

Dieses Anti-PRMT6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRMT6 in WB und IHC. Geeignet für Human.

Kurzübersicht für PRMT6 Antikörper (N-Term) (ABIN6972556)

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PRMT6 Antikörper

Bindungsspezifität: N-Term

Produktmerkmale: PRMT6 (Protein Arginine Methyltransferase 6, HRMT1L6, ANM6) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT6 preferentially methylates arginine residues present in GAR (glycine and arginine-rich) domains. PRMT6 asymmetrically dimethylates histone H3 at Arg2, which is mutually exclusive to methylation at lysine 4 (associated with transcriptional activation), and thus PRMT6 serves as a transcriptional repressor in this context. It can also symmetrically dimethylate H2A and H4 at Arg3 and serves as a coactivator of transcription in concert with nuclear receptors. PRMT6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunohistochemistry and Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This PRMT6 antibody was raised against a peptide corresponding to amino acids within the N-terminal region of PRMT6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Andere Bezeichnung: PRMT6

Molekulargewicht: 42 kDa

NCBI Accession: NP_060607