PHF6 Antikörper (Isoform 1, N-Term)
Kurzübersicht für PHF6 Antikörper (Isoform 1, N-Term) (ABIN6972521)
Target
Alle PHF6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Isoform 1, N-Term
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Produktmerkmale
- PHF6 is a member of the plant homeodomain finger (PHF) family, which has a potential rode in regulation of chromatin accessibility to lineage-specific transcription factors as part of the nucleosome remodeling and deacetylase (NuRD) epigenetic complex. PHF6 has been reported as a tumor suppressor in association with hematopoietic malignancies including T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (AML). PHF6 may have tissue-specific expression, and is overexpressed in both breast and colorectal cancers. Germline mutations in PHF6 are the cause of the Börjeson-Forssman-Lehmann X-linked intellectual disability syndrome (BFLS). PHF6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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Aufreinigung
- Affinity Purified
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Immunogen
- This antibody was generated using a peptide from the N-terminal region of human PHF6 (PHD finger protein 6 isoform 1).
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- PHF6 (PHD Finger Protein 6 (PHF6))
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Andere Bezeichnung
- PHF6
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Molekulargewicht
- 45 kDa
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NCBI Accession
- NP_115834
Target
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