MED15 Antikörper (C-Term)

Produktnummer ABIN6972333

Der Kaninchen Polyklonal Anti-MED15-Antikörper wurde für WB und IP validiert. Er ist geeignet, MED15 in Proben von Human zu detektieren.

Kurzübersicht für MED15 Antikörper (C-Term) (ABIN6972333)

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-MED15 Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: MED15 (mediator of RNA polymerase II transcription subunit 15) is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. MED15 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of human MED15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu MED15

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Andere Bezeichnung: MED15

Molekulargewicht: 100 kDa

NCBI Accession: NP_001003891

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha