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MED1 Antikörper (C-Term)

Dieses Anti-MED1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MED1 in WB und IP. Geeignet für Human.
Produktnummer ABIN6972331

Kurzübersicht für MED1 Antikörper (C-Term) (ABIN6972331)

Target

Alle MED1 Antikörper anzeigen
MED1 (Mediator Complex Subunit 1 (MED1))

Reaktivität

  • 56
  • 28
  • 12
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
Human

Wirt

  • 50
  • 4
  • 2
  • 1
Kaninchen

Klonalität

  • 52
  • 5
Polyklonal

Konjugat

  • 32
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MED1 Antikörper ist unkonjugiert

Applikation

  • 28
  • 24
  • 14
  • 13
  • 13
  • 13
  • 9
  • 7
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • Bindungsspezifität

    • 15
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Produktmerkmale

    MED1 (Mediator complex subunit 1, TRIP2, Thyroid receptor-interacting protein 2) is a component of the Mediator complex, a coactivator involved in the regulated transcription of most genes transcribed by RNA polymerase II. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. MED1 is involved in supporting hematopoietic stem and/or progenitor cell function. MED1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

    Aufreinigung

    Affinity Purified

    Immunogen

    This MED1 antibody was raised against a peptide within the C-terminal region of human MED1.

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target

    MED1 (Mediator Complex Subunit 1 (MED1))

    Andere Bezeichnung

    MED1

    Molekulargewicht

    210 kDa

    NCBI Accession

    NP_004765

    Pathways

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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