IRF2 Antikörper (C-Term)

Produktnummer ABIN6972209

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IRF2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IRF2 Antikörper (C-Term) (ABIN6972209)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRF2 Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: IRF-2 (interferon regulatory factor 2) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. IRF-2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This IRF-2 antibody was raised against a peptide within the C-terminal region of human IRF-2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Andere Bezeichnung: IRF-2

Molekulargewicht: 39 kDa

NCBI Accession: NP_002190