HIRA Antikörper (AA 421-729)

Produktnummer ABIN6971732

Dieser Maus Monoklonal Antikörper erkennt spezifisch HIRA in WB, IF und ICC. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für HIRA Antikörper (AA 421-729) (ABIN6971732)

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: WC119-2H11

Produktdetails anti-HIRA Antikörper

Bindungsspezifität: AA 421-729

Produktmerkmale: HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1a is involved in the formation of the senescence-associated heterochromatin foci. HIRA antibody (mAb) (Clone WC119.2H11) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Protein G Chromatography

Immunogen: This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu HIRA

Target: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Andere Bezeichnung: HIRA

Molekulargewicht: 120 kDa

NCBI Accession: NP_003316

Pathways: Chromatin Binding