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GLYR1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-GLYR1-Antikörper wurde für WB validiert. Er ist geeignet, GLYR1 in Proben von Human zu detektieren.
Produktnummer ABIN6971688

Kurzübersicht für GLYR1 Antikörper (C-Term) (ABIN6971688)

Target

Alle GLYR1 Antikörper anzeigen
GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Reaktivität

  • 29
  • 25
  • 10
Human

Wirt

  • 27
  • 2
Kaninchen

Klonalität

  • 29
Polyklonal

Konjugat

  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GLYR1 Antikörper ist unkonjugiert

Applikation

  • 21
  • 13
  • 13
  • 6
  • 3
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 2
    • 1
    • 1
    C-Term

    Produktmerkmale

    GLYR1 / NDF (nucleosome-destabilizing factor) that is recruited to gene bodies during transcriptional activation and facilitates Pol II transcription through nucleosomes, where it is proposed to ""unzip"" chromatin during transcription, pushing the polymerase past pause points. It was discovered as a factor that allows p300 to acetylate Histone H3K56, which is normally an inaccessible residue for this modification. GLYR1 is shown to associate with a subset of highly transcribed genes tending to have longer mRNAs rather than shorter, and is also at a significant subset of loci containing the Histone H3K36me3. GLYR1 is expressed at high levels in most tissue types, including stem cells, and has been found to be overexpressed in breast cancer. GLYR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

    Aufreinigung

    Affinity Purified

    Immunogen

    This antibody was raised against a peptide within the C-terminal region of human GLYR1.

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 30 % glycerol, and 0.035 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target

    GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

    Andere Bezeichnung

    GLYR1

    Molekulargewicht

    65 kDa

    NCBI Accession

    NP_115958
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