CoREST Antikörper (C-Term)

Produktnummer ABIN6971547

Der Kaninchen Polyklonal Anti-CoREST-Antikörper wurde für WB validiert. Er ist geeignet, CoREST in Proben von Human zu detektieren.

Kurzübersicht für CoREST Antikörper (C-Term) (ABIN6971547)

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CoREST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CoREST Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: CoREST (REST corepressor 1, RCOR1) is a corepressor protein recruited by the REST, a neuronal gene-specific transcriptional repressor, to help repress neuron specific gene expression in non-neuronal cell lineages. CoREST is an essential component of the BHC repressor complex that also contains HDAC1, HDAC2, HMG20B/BRAF35, LSD1 (a lysine-4 specific histone demethylase) and PHF21A/BHC80. The Herpes Simplex virus ICP0 protein blocks the repression of viral genes by disrupting the interaction between CoREST and HDAC1/2. CoREST antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This CoREST antibody was raised against a synthetic peptide derived from the C-terminal region of human CoREST.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu CoREST

Target: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Andere Bezeichnung: CoREST

Molekulargewicht: 66 kDa

NCBI Accession: NP_055971

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding