CHD1 Antikörper (C-Term)

Produktnummer ABIN6971529

Produktdetails anti-CHD1 Antikörper

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktmerkmale: CHD1 (Chromo-ATPase/Helicase-DNA-binding protein 1 ) is a member of the CHD family of ATP-dependent chromatin remodeling factors implicated in RNA polymerase II transcriptional regulation. They are characterized by the presence of a double chromodomains (Chromatin Organization Modifier) and SNF2-related helicase/ATPase domains. The CHD1/CHD2 sub-family of CHD proteins also contain a C-terminal DNA binding domain that recognizes AT-rich sequences. CHD proteins alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD1 has been shown to interact with histone H3 trimethylated at lysine 4 (H3K4Me3) and also is required for the maintenance of stem cell pluripotency. CHD1 antibody (mAb) (Clone 2F11) was raised in a Rat host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Protein G Chromatography

Immunogen: This CHD1 antibody was raised against a peptide corresponding to the C-terminus of mouse CHD1.

Klon: 2F11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Andere Bezeichnung: CHD1 (CHD1 Produkte)

Synonyme: CHD-1 antikoerper, 4930525N21Rik antikoerper, AI851787 antikoerper, AW555109 antikoerper, CHD1 antikoerper, CG3733 antikoerper, DmCHD1 antikoerper, Dmel\\CG3733 antikoerper, chd1 antikoerper, dCHD1 antikoerper, l(2)23Cd antikoerper, CHD1W antikoerper, chromodomain helicase DNA binding protein 1 antikoerper, Chromodomain-helicase-DNA-binding protein antikoerper, Chromodomain-helicase-DNA-binding protein 1 antikoerper, CHD1 antikoerper, Chd1 antikoerper, CHDB1 antikoerper

Molekulargewicht: 210 kDa

NCBI Accession: NP_031716

Pathways: Chromatin Binding