ATRX Antikörper (C-Term)

Produktnummer ABIN6971417

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATRX in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ATRX Antikörper (C-Term) (ABIN6971417)

Target: ATRX (helicase 2, X-linked (ATRX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATRX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATRX Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: ATRX (alpha thalassemia/mental retardation syndrome X-linked protein, X-linked helicase II, XNP) is a transcriptional regulator and a member of the SWI/SNF family of chromatin remodeling proteins. It contains an SNF2 domain and helicase domain, and a PHD finger. ATRX undergoes cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in interphase gene regulation and chromosomal segregation in mitosis. Mutations of the ATRX gene are associated with an X-linked mental retardation syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. ATRX antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This ATRX antibody was raised against a peptide within the C-terminus of human ATRX.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu ATRX

Target: ATRX (helicase 2, X-linked (ATRX))

Andere Bezeichnung: ATRX

Molekulargewicht: 300 kDa

NCBI Accession: NP_000480