Interleukin 17a Antikörper

Produktnummer ABIN6964028

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Interleukin 17a in Neut. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Interleukin 17a Antikörper (ABIN6964028)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interleukin 17a Antikörper ist unkonjugiert

Applikation: Neutralization (Neut)

Klon: MT504

Produktdetails anti-Interleukin 17a Antikörper

Spezifität: Native and recombinant IL-17A.

Kreuzreaktivität (Details): The antibody cross-reacts with IL-17A from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-17A

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Neutralization of human IL-17A bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-17A induced IL-6 production (see graph). To determine the neutralizing capacity and ND50, various concentrations of mAb MT504 and human recombinant IL-17A were added to normal human dermal fibroblasts. Following overnight incubation, cell supernatants were quantified in IL-6 ELISA. Neutralization dose 50 (ND50): MT504 neutralized the effect of IL-17A at a ND50value of 0.01-0.03 μg/mL when 10 ng/mL IL-17A was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS free of preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Haltbarkeit: 18 months

Details zu Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Andere Bezeichnung: IL17A

Gen-ID: 3605