IL23 Antikörper

Produktnummer ABIN6964023

Der Maus Monoklonal Anti-IL23-Antikörper wurde für Neut validiert. Er ist geeignet, IL23 in Proben von Human zu detektieren.

Kurzübersicht für IL23 Antikörper (ABIN6964023)

Target: IL23 (Interleukin 23 (IL23))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL23 Antikörper ist unkonjugiert

Applikation: Neutralization (Neut)

Klon: MT155

Produktdetails anti-IL23 Antikörper

Spezifität: Native and recombinant IL-23. The antibody recognizes the p19 subunit of the IL-23 heterodimer (p40+p19).

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-23

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Neutralization of human IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays. Neutralization Neutralization assay: Neutralization of human IL-23 induced IFN-γ production (see graph). To determine the neutralizing capacity and ND50, mixtures of various concentrations of mAb MT155, human recombinant IL-23 (10 ng/mL) and recombinant human IL-18 (50 ng/mL) were added to human PBMC. Following overnight incubation, cell supernatants were quantified in IFN-γ ELISA. Neutralization dose 50 (ND50): MT155 neutralized the effect of IL-23 at a ND50value of 0.2-0.8 μg/mL when 10 ng/mL recombinant human IL-23 was present. ND50 is defined as the concentration of antibody that results in 50 % inhibition of the biological response under the experimental conditions specified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Haltbarkeit: 18 months

Details zu IL23

Target: IL23 (Interleukin 23 (IL23))

Andere Bezeichnung: IL23

Gen-ID: 51561