KLRG1 Antikörper
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- Target Alle KLRG1 Antikörper anzeigen
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
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Reaktivität
- Maus
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Wirt
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Golden Syrian Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser KLRG1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Aufreinigung
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- Klon
- 2F1
- Isotyp
- IgG
- Top Product
- Discover our top product KLRG1 Primärantikörper
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- Applikationshinweise
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- Kommentare
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0.5 mg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- 2-8°C
- Haltbarkeit
- 12 months
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- Target
- KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))
- Andere Bezeichnung
- KLRG1 (KLRG1 Produkte)
- Synonyme
- KLRG1 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, 2F1 antikoerper, CLEC15A antikoerper, MAFA-2F1 antikoerper, MAFA-LIKE antikoerper, killer cell lectin like receptor G1 antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, KLRG1 antikoerper, Klrg1 antikoerper
- Hintergrund
- The 2F1 antibody reacts with mouse KLRG1 (Killer cell Lectin-like Receptor G1). This 30-38 kDa homodimeric receptor may be expressed by activated, mature NK cells and by effector/memory T cells, with potentially different roles in each cell type. KLRG1 can regulate, in an inhibitory fashion, the development and effector functions of NK cells, and is often cited as a senescence or terminal differentiation marker for T cells. Ligands for KLRG1 include members of the cadherin family of adhesion molecules, specifically N-Cadherin, E-Cadherin, and R-Cadherin. These interactions may induce bidirectional, immunosuppressive signaling in both KLRG- and Cadherin-expressing cells. A more recently identified role for KLRG1-Cadherin signaling in tissue organization, e.g. in cardiac angiogenesis, expands the function of these interactions beyond immunosuppression of immune cells. (Bouchentouf et al. 2010. J. Immunol. 185: 7014-7025).The 2F1 antibody may be used as a phenotypic marker for KLRG1 in mouse, frequently in combination with Anti-Mouse CD127 antibody (clone A7R34), for identification of effector T cell populations.
- Gen-ID
- 50928
- UniProt
- O88713
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