SARS-CoV-2 Nucleocapsid Antikörper
Kurzübersicht für SARS-CoV-2 Nucleocapsid Antikörper (ABIN6953169)
Target
Alle SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Monoclonal Antibody to SARS-CoV-2 Nucleocapsid Protein
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Spezifität
- This antibody and its recommended antibody pair have been proven to detect all known SARS-CoV-2 variants such as Omicron variant (B1.1.529), Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2). This antibody is used in several regulated immunoassays worldwide.
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Kreuzreaktivität (Details)
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This antibody does not cross react with:
- MERS-coronavirus
- Human coronavirus (NL63, 229E, OC43)
- Human Adenovirus (type 1, 3, 5, 7, 8, 11, 18, 23)
- Human Parainfluenza virus (type 1, 2, 3, 4)
- Human Rhinovirus (type 1, 14, 42)
- Human Metapneumovirus
- Respiratory syncytial virus-A
- Respiratory syncytial virus-B
This antibody does cross react with SARS-CoV.
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Produktmerkmale
- The performance of a rapid antigen test is limited by the sensitivity of the antibodies used. The new pair of monoclonal antibodies is highly sensitive for the detection of SARS-CoV-2 Nucleoprotein and they do not cross-react with seasonal coronavirus strains. They are ideal for developing reliable and sensitive rapid lateral flow antigen assays for the detection of active COVID-19 infections.
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Aufreinigung
- Protein A Chromatography
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Reinheit
- > 95 % (SDS-PAGE)
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Immunogen
- Recombinant SARS-CoV-2 Nucleocapsid Protein
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Isotyp
- IgG1
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Applikationshinweise
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Each laboratory should determine an optimum working titer for use in its particular application.
Recommended pair for Immunoassay:Capture - Detection
- ABIN6953170 - ABIN6953169
- ABIN6953170 - ABIN6953295
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Kommentare
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An FDA-approved COVID-19 lateral flow assay using the SARS-CoV-2 nucleocapsid antibody pair (ABIN6953170 + ABIN6953169 ) shows that the pair can detect the Omicron variant (live virus of B.1.1.529) up to 1.31 x 10^2 PFU/mL, and other variants up to 1.88 x 10^2 PFU/mL. The two antibodies recognize the conserved nucleoprotein domain of SARS-CoV-2 and are already used in many commercially available COVID-19 antigen rapid tests around the world.
These two antibodies work as a High-Sensitivity SARS-CoV-2 Nucleoprotein Antibody Pair for Rapid COVID-19 Antigen Assays: ABIN6953170, ABIN6953169
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 4.8 mg/mL
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Buffer
- Phosphate Buffered Saline, pH 7.4, 0.05 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C
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- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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Andere Bezeichnung
- SARS-CoV-2 Nucleocapsid Protein
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Substanzklasse
- Viral Protein
Target
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