SARS-CoV-2 Nucleocapsid Antikörper
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- Target Alle SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Antikörper anzeigen
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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Reaktivität
- SARS Coronavirus-2 (SARS-CoV-2)
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SARS-CoV-2 Nucleocapsid Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Aufreinigung
- Purified by Protein G.
- Klon
- 14B2D
- Isotyp
- IgG2b
- Top Product
- Discover our top product SARS-CoV-2 N Primärantikörper
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- Applikationshinweise
- WB(1:500-2000), ELISA(1:500-1000)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- ≥ 1 mg/mL
- Buffer
- 0.01M PBS( pH 7.4) with 0.1 % Proclin300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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- Target
- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
- Andere Bezeichnung
- SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N Produkte)
- Synonyme
- nucleocapsid phosphoprotein antikoerper, N antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
- Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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