SARS-CoV-2 Nucleocapsid Antikörper
Kurzübersicht für SARS-CoV-2 Nucleocapsid Antikörper (ABIN6952935)
Target
Alle SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Purified by Protein G.
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Isotyp
- IgG2b
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Applikationshinweise
- WB(1:500-2000), ELISA(1:500-1000)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- ≥ 1 mg/mL
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Buffer
- 0.01M PBS( pH 7.4) with 0.1 % Proclin300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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Andere Bezeichnung
- SARS-CoV-2 Nucleocapsid Protein
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Substanzklasse
- Viral Protein
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Hintergrund
- Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Target
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