EZH2 Antikörper (AA 1-343)
Kurzübersicht für EZH2 Antikörper (AA 1-343) (ABIN6952425)
Target
Alle EZH2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 1-343
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Spezifität
- Polyclonal antibody raised in rabbit against the N-terminus (aa1-343) of the mouse EZH2 protein (Enhancer of zeste homolog 2).
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Kreuzreaktivität
- Maus
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Aufreinigung
- Protein G purified
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Immunogen
- recombinant protein
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Applikationshinweise
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ChIP/ChIP-seq 2 μg:ChIP
WB 1:1,000
IF 1:1,000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- PBS, 0.05 % azide, 0.05 % ProClin300
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
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Andere Bezeichnung
- EZH2
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Hintergrund
- EZH2 (UniProt/Swiss-Prot entry Q15910) is a histone-lysine methyltransferase which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression. It is a member of the polycomb group (PcG) family which form multimeric protein complexes and are involved in maintaining the transcriptional repressive state of genes over successive cell generations. The EZH2 activity is dependent on the association with other components of the PRC2 complex (EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7). EZH2 may play a role in the hematopoietic and central nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer.
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UniProt
- Q15910
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
Target
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