Polyclonal antibody raised in rabbit against human KAT2B (Lysine Acetyltransferase 2B), using a synthetic peptide containing a sequence from the C-terminal part of the protein.
KAT2B
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB14386
unconjugated
Applikationshinweise
ChIP/ChIP-seq 2 μg:ChIP WB 1:1,000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 μg/μL
Buffer
Tris-citrate/phosphate buffer, 0.05 % azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
KAT2B
(K(lysine) Acetyltransferase 2B (KAT2B))
Andere Bezeichnung
KAT2B
Hintergrund
KAT2B (UniProtKB/Swiss-Prot entry Q92831) functions as a histone acetyltransferase, thereby promoting transcriptional activation. KAT2B binds with CBP and p300 where it competes with the adenoviral oncoprotein E1A for binding sites and as such counteracts the mitogenic activity of E1A. KAT2B also acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.