POLR2A/RPB1 Antikörper (pSer2)
Kurzübersicht für POLR2A/RPB1 Antikörper (pSer2) (ABIN6952399)
Target
Alle POLR2A/RPB1 (POLR2A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- pSer2
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Spezifität
- Monoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II, phosphorylated at Ser2 of the repeat sequence.
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Kreuzreaktivität
- Zebrafisch (Danio rerio)
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Aufreinigung
- Protein A purified
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Isotyp
- IgG1
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Applikationshinweise
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ChIP/ChIP-seq 1 - 2 μg:ChIP
ELISA 1:3,000
WB 1:1,000
IF 1:500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- PBS, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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Andere Bezeichnung
- Pol II
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Hintergrund
- RNA polymerase II (pol II) is a key enzyme in the regulation and control of gene transcription. It is able to unwind the DNA double helix, synthesize RNA, and proofread the result. Pol II is a complex enzyme, consisting of 12 subunits, of which the B1 subunit (UniProt/Swiss-Prot entry P24928) is the largest. Together with the second largest subunit, B1 forms the catalytic core of the RNA polymerase II transcription machinery.
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UniProt
- P24928
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Pathways
- Regulatorische RNA Pathways
Target
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