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tau Antikörper (Biotin)

Reaktivität: Human WB, ELISA, IF, ICC, DB Wirt: Maus Monoclonal 1D5 Biotin
Produktnummer ABIN6952089
  • Target Alle tau Antikörper anzeigen
    tau (tau Protein)
    Reaktivität
    • 524
    • 501
    • 499
    • 40
    • 28
    • 27
    • 18
    • 6
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 630
    • 35
    • 2
    • 1
    Maus
    Klonalität
    • 605
    • 62
    • 1
    Monoklonal
    Konjugat
    • 209
    • 39
    • 34
    • 33
    • 33
    • 33
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    • 32
    • 30
    • 24
    • 24
    • 24
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    • 24
    • 13
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser tau Antikörper ist konjugiert mit Biotin
    Applikation
    • 548
    • 272
    • 263
    • 204
    • 92
    • 85
    • 68
    • 59
    • 52
    • 35
    • 33
    • 16
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)
    Spezifität
    Expressed in neurons.,Detects Multiple Bands. Antibody detects monomer under denaturing conditions but preferentially detects fibril under native conditions (dot blot).
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Protein G Purified
    Immunogen
    Human Recombinant Tau441 (2N4R), P301S mutant Protein Pre-formed Fibrils
    Klon
    1D5
    Isotyp
    IgG1
    Top Product
    Discover our top product tau Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN6952089 was sufficient for detection of Tau 2N4R P301S Fibril in 20 ug of Mouse Brain by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    tau (tau Protein)
    Andere Bezeichnung
    Tau (tau Produkte)
    Synonyme
    DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper
    Hintergrund
    Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). 2N4R, or Tau-441 is the full length tau protein. P301S is a mutation encoded by exon 10 (4) that impairs the ability of tau to assemble microtubules (5).
    NCBI Accession
    NP_005901
    UniProt
    P10636
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