TGFBR1 Antikörper

Produktnummer ABIN6950907

Der Maus Monoklonal anti-TGFBR1 Antikörper (ABIN6950907) detektiert spezifisch TGFBR1 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für TGFBR1 Antikörper (ABIN6950907)

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TGFBR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-TGFBR1 Antikörper

Verwendungszweck: TGF β Receptor I mouse mAb

Spezifität: The antibody can specifically recognize human TGF β Receptor I protein.

Aufreinigung: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 34 - 100 of the human TGF beta Receptor I protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu TGFBR1

Target: TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Andere Bezeichnung: TGF beta Receptor I

Hintergrund:

Synonyms: AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, TBRI, ALK-5, LDS1A, LDS2A, TBR-i, TGFR-1, ACVRLK4, tbetaR-I, TGF beta Receptor I (TGFBR1)

Background: Members of the transforming growth factor β (TGF-β) superfamily are key regulators of cell proliferation, differentiation, development, morphogenesis, and disease pathogenesis. TGF-β signals through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form heteromeric complexes. Upon ligand binding, type II receptors form a stable complex with type I receptors, leading to phosphorylation and activation of the type I receptor kinase.

Gene Name: TGFBR1 ALK5 SKR4

Protein Name: TGF β Receptor I

Gen-ID: 7046

UniProt: P36897

Pathways: Growth Factor Binding