Claudin 18 Antikörper
Kurzübersicht für Claudin 18 Antikörper (ABIN6950837)
Target
Alle Claudin 18 (CLDN18) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Claudin 18 mouse mAb
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Spezifität
- The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.
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Aufreinigung
- The antibody was purified by affinity chromatography using a specific immunogen.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.
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Isotyp
- IgG
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anti-Claudin 18 (CLDN18) (AA 31-261) antibody
CLDN18 Reaktivität: Human, Ratte WB, IHC, ELISA, FACS, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (C-Term) antibodyCLDN18 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (AA 196-261) antibodyCLDN18 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (AA 20-80) antibodyCLDN18 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (C-Term) antibodyCLDN18 Reaktivität: Human, Ratte, Hund, Pferd, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (AA 143-192) antibodyCLDN18 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Affe, Schwein, Huhn WB Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) antibodyCLDN18 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal unconjugated
anti-Claudin 18 (CLDN18) (C-Term) antibodyCLDN18 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (AA 196-261) antibodyCLDN18 Reaktivität: Human ELISA, WB Wirt: Maus Polyclonal unconjugated
anti-Claudin 18 (CLDN18) (C-Term) antibodyCLDN18 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IHC, 1:200-1:400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at-20°C. Avoid freeze / thaw cycles.
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- Claudin 18 (CLDN18)
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Andere Bezeichnung
- Claudin 18
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Hintergrund
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Synonyms: Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ
Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.
Gene Name: CLDN18
Protein Name: Claudin 18
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Gen-ID
- 51208
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UniProt
- P56856
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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