Rekombinanter PRNP Antikörper

Produktnummer ABIN6944654

Der Kaninchen Monoklonal anti-PRNP Antikörper (ABIN6944654) detektiert spezifisch PRNP in WB, FACS, IF (cc), IF (p), IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter PRNP Antikörper (ABIN6944654)

Target: PRNP (Prion Protein (PRNP))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PRNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PRNP Antikörper

Verwendungszweck: PRNP Recombinant Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: C terminal human Prion protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(WB(1:500-2000)), FCM(FCM(1:50-100)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)), IF(IHC-P)(IF(IHC-P)(1:50-200)), IF(ICC)(IF(ICC)(1:50-200))

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PRNP

Target: PRNP (Prion Protein (PRNP))

Andere Bezeichnung: Prion Protein (PrP)

Hintergrund:

Synonyms: Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP

Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

Gen-ID: 5621

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation