PRNP Antikörper
Kurzübersicht für PRNP Antikörper (ABIN6944654)
Target
Alle PRNP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- C terminal human Prion protein
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- PRNP (Prion Protein (PRNP))
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Andere Bezeichnung
- Prion Protein (PrP)
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Hintergrund
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Synonyms: Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP
Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
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Gen-ID
- 5621
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UniProt
- P04156
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Pathways
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
Target
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