tau Antikörper (pThr231)
-
- Target Alle tau Antikörper anzeigen
- tau (tau Protein)
-
Bindungsspezifität
- pThr231
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser tau Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Synthetic phospho-peptide surrounding Thr231 of human Tau
- Klon
- 13D4
- Isotyp
- IgG
- Top Product
- Discover our top product tau Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IF(ICC) 1:50-200
IHC() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
-
- Target
- tau (tau Protein)
- Andere Bezeichnung
- Tau (tau Produkte)
- Synonyme
- DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper
- Hintergrund
-
Synonyms: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
- Gen-ID
- 4137
- UniProt
- P10636
-