RPS19 Antikörper

Produktnummer ABIN6944797

Der Kaninchen Monoklonal Anti-RPS19-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, RPS19 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für RPS19 Antikörper (ABIN6944797)

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RPS19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1C1

Produktdetails anti-RPS19 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Full length recombinant protein of RPS19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RPS19

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Andere Bezeichnung: RPS19

Hintergrund:

Synonyms: 40S ribosomal protein S19, Small ribosomal subunit protein eS19, RPS19.

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 is a ribosomal protein that is a component of the 40S subunit. RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gen-ID: 6223

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly