PEN2 Antikörper (C-Term)
Kurzübersicht für PEN2 Antikörper (C-Term) (ABIN6944688)
Target
Alle PEN2 (PSENEN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Verwendungszweck
- PSENEN (1D8) Monoclonal Antibody
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Synthetic peptide corresponding to C-terminal human PEN2.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Andere Bezeichnung
- PSENEN
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Hintergrund
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Synonyms: Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN, PEN2, presenilin enhancer gamma-secretase subunit, MDS033
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
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Gen-ID
- 55851
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UniProt
- Q9NZ42
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Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
Target
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