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Pro Caspase 9 Antikörper

Reaktivität: Human FACS, WB Wirt: Kaninchen Monoclonal 3T6 unconjugated
Produktnummer ABIN6944661
  • Target
    Pro Caspase 9
    Reaktivität
    Human
    Wirt
    • 7
    Kaninchen
    Klonalität
    • 7
    Monoklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    Flow Cytometry (FACS), Western Blotting (WB)
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Human Caspase-9 between 250 to 350 amino acids
    Klon
    3T6
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Pro Caspase 9
    Hintergrund

    Synonyms: Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9

    Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

    Gen-ID
    842
    UniProt
    P55211
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