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PKC mu Antikörper

PRKD1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Monoclonal 10C1 unconjugated
Produktnummer ABIN6944657
  • Target Alle PKC mu (PRKD1) Antikörper anzeigen
    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
    Reaktivität
    • 128
    • 84
    • 72
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 141
    • 2
    • 2
    Kaninchen
    Klonalität
    • 136
    • 9
    Monoklonal
    Konjugat
    • 67
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Dieser PKC mu Antikörper ist unkonjugiert
    Applikation
    • 96
    • 47
    • 40
    • 40
    • 29
    • 17
    • 15
    • 10
    • 6
    • 6
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Human PKC mu aa 500-650
    Klon
    10C1
    Isotyp
    IgG
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    Discover our top product PRKD1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
    Andere Bezeichnung
    PRKD1 (PRKD1 Produkte)
    Synonyme
    MGC83727 antikoerper, PRKD1 antikoerper, pkd antikoerper, pkcm antikoerper, prkcm antikoerper, pkc-mu antikoerper, PKC-MU antikoerper, PKCM antikoerper, PKD antikoerper, PRKCM antikoerper, PKD1 antikoerper, Pkcm antikoerper, Prkcm antikoerper, nPKC-D1 antikoerper, nPKC-mu antikoerper, PKC antikoerper, protein kinase D1 antikoerper, protein kinase D1 L homeolog antikoerper, PRKD1 antikoerper, prkd1.L antikoerper, prkd1 antikoerper, Prkd1 antikoerper
    Hintergrund

    Synonyms: Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKC mu, CHDED.

    Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

    Gen-ID
    5587
    UniProt
    Q15139
    Pathways
    Myometrial Relaxation and Contraction
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