PKC mu Antikörper

Produktnummer ABIN6944657

Dieser Anti-PKC mu Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von PKC mu in WB und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für PKC mu Antikörper (ABIN6944657)

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PKC mu Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 10C1

Produktdetails anti-PKC mu Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Human PKC mu aa 500-650

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PKC mu

Target: PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

Andere Bezeichnung: PRKD1

Hintergrund:

Synonyms: Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKC mu, CHDED.

Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

Gen-ID: 5587

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction