PMP22 Antikörper

Produktnummer ABIN6944620

Der Kaninchen Monoklonal Anti-PMP22-Antikörper wurde für WB, IF (cc), IF (p), IHC (p) und FACS validiert. Er ist geeignet, PMP22 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für PMP22 Antikörper (ABIN6944620)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PMP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 1A11

Produktdetails anti-PMP22 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Full length protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Andere Bezeichnung: PMP22

Hintergrund:

Synonyms: Peripheral myelin protein 22, Growth arrest-specific protein 3, PMP-22, GAS-3, PMP22, GAS3

Background: PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.

Gen-ID: 5376

UniProt: Q01453