NQO1 Antikörper (AA 201-274) (Biotin)

Produktnummer ABIN6944312

Produktdetails anti-NQO1 Antikörper (Biotin)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Bindungsspezifität: AA 201-274

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NQO1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NQO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Andere Bezeichnung: NQO1 (NQO1 Produkte)

Synonyme: zgc:77191 antikoerper, wu:fb63c10 antikoerper, nqo1 antikoerper, DHQU antikoerper, DIA4 antikoerper, DTD antikoerper, NMOR1 antikoerper, NMORI antikoerper, QR1 antikoerper, Dia4 antikoerper, AV001255 antikoerper, Dtd antikoerper, Nmo-1 antikoerper, Nmo1 antikoerper, Nmor1 antikoerper, Ox-1 antikoerper, Ox1 antikoerper, Qr1 antikoerper, NADPH-d antikoerper, NAD(P)H dehydrogenase, quinone 1 antikoerper, NAD(P)H quinone dehydrogenase 1 antikoerper, NAD(P)H dehydrogenase, quinone 1 L homeolog antikoerper, nqo1 antikoerper, NQO1 antikoerper, Bpet2092 antikoerper, nqo1.L antikoerper, Nqo1 antikoerper

Hintergrund:

Synonyms: Azoreductase, Cytochrome b 5 reductase, DHQU, DIA 4, DIA4, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH) (cytochrome b-5 reductase), Diaphorase (NADH/NADPH), Diaphorase 4, Dioxin inducible 1, DT diaphorase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H dehydrogenase quinone 1, NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I, NMOR1, NMORI, NQO 1, NQO1, NQO1_HUMAN, Phylloquinone reductase, Phylloquinone reductase, QR 1, QR1, Quinone reductase 1, Quinone reductase 1.

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Gen-ID: 18104

UniProt: Q64669