MDFI Antikörper (AA 101-200) (Cy7)

Produktnummer ABIN6944059

Der Kaninchen Polyklonal Anti-MDFI-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, MDFI in Proben von Human zu detektieren.

Kurzübersicht für MDFI Antikörper (AA 101-200) (Cy7) (ABIN6944059)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFI Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MDFI Antikörper (Cy7)

Bindungsspezifität: AA 101-200

Spezifität: In Mice, there is possible cross-reactivity with Glycoprotein endo-alpha-1,2-mannosidase (67 % homology with immunogen sequence, 53 kDa)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MDFI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Andere Bezeichnung: MDFI

Hintergrund:

Synonyms: I MF, I mfa, Inhibitor of MyoD family a, Mdfi, MDFI_HUMAN, MyoD family inhibitor, Myogenic repressor I-mf, OTTHUMP00000016375, OTTHUMP00000016376, OTTHUMP00000196103, OTTHUMP00000196414, OTTHUMP00000196415.

Background: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

Gen-ID: 4188

UniProt: Q99750

Pathways: Maintenance of Protein Location