MARK3 Antikörper

Produktnummer ABIN6944028

Produktdetails anti-MARK3 Antikörper

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MARK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human Mark3 aa 600-750.

Klon: 2F7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu MARK3

Target: MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))

Andere Bezeichnung: MARK3 (MARK3 Produkte)

Synonyme: MARK3 antikoerper, par1 antikoerper, par-1 antikoerper, Par-1A antikoerper, CTAK1 antikoerper, KP78 antikoerper, PAR1A antikoerper, Par-1a antikoerper, 1600015G02Rik antikoerper, A430080F22Rik antikoerper, C-TAK1 antikoerper, ETK-1 antikoerper, ETK1 antikoerper, Emk2 antikoerper, MPK10 antikoerper, fi39g08 antikoerper, wu:fi39g08 antikoerper, zgc:152848 antikoerper, zgc:55693 antikoerper, c-tak1 antikoerper, ctak1 antikoerper, emk-2 antikoerper, microtubule affinity regulating kinase 3 antikoerper, MAP/microtubule affinity-regulating kinase 3b antikoerper, MAP/microtubule affinity regulating kinase 3 antikoerper, MAP/microtubule affinity-regulating kinase 3a antikoerper, microtubule affinity regulating kinase 3 L homeolog antikoerper, MARK3 antikoerper, mark3b antikoerper, mark3 antikoerper, Mark3 antikoerper, mark3a antikoerper, mark3.L antikoerper

Hintergrund:

Synonyms: MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, microtubule affinity regulating kinase 3

Background: Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.

Gen-ID: 4140

UniProt: P27448

Pathways: SARS-CoV-2 Protein Interaktom