MARK3 Antikörper (AA 600-750)
Kurzübersicht für MARK3 Antikörper (AA 600-750) (ABIN6944028)
Target
Alle MARK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 600-750
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Verwendungszweck
- MARK3 Recombinant Antibody
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Kreuzreaktivität
- Human
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Homologie
- Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant protein within human Mark3 aa 600-750.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:500-2000), FCM(1:50-100)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))
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Andere Bezeichnung
- MARK3
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Hintergrund
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Synonyms: MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, microtubule affinity regulating kinase 3
Background: Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.
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Gen-ID
- 4140
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UniProt
- P27448
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
-