LGALS8 Antikörper
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- Target Alle LGALS8 Antikörper anzeigen
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser LGALS8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Synthetic peptide within human Galectin 8 aa 1-100
- Klon
- 1A4
- Isotyp
- IgG
- Top Product
- Discover our top product LGALS8 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
- Andere Bezeichnung
- LGALS8 (LGALS8 Produkte)
- Synonyme
- LGALS8 antikoerper, 1200015E08Rik antikoerper, AI326142 antikoerper, D13Ertd524e antikoerper, Lgals-8 antikoerper, galectin-8 antikoerper, Gal-8 antikoerper, PCTA-1 antikoerper, PCTA1 antikoerper, Po66-CBP antikoerper, xgalectin-VIIIa antikoerper, galectin 8 antikoerper, lectin, galactose binding, soluble 8 antikoerper, lectin, galactoside binding soluble 8 S homeolog antikoerper, LGALS8 antikoerper, Lgals8 antikoerper, lgals8.S antikoerper
- Hintergrund
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Synonyms: Galectin-8, Po66 carbohydrate-binding protein, Prostate carcinoma tumor antigen 1, Gal-8, Po66-CBP, PCTA-1, LGALS8
Background: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.
- Gen-ID
- 3964
- UniProt
- O00214
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