MYST1 Antikörper
-
- Target Alle MYST1 (KAT8) Antikörper anzeigen
- MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MYST1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within N-terminal human KAT8.
- Klon
- 2B1
- Isotyp
- IgG
- Top Product
- Discover our top product KAT8 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
- Andere Bezeichnung
- KAT8 (KAT8 Produkte)
- Synonyme
- myst1 antikoerper, wu:fb22g02 antikoerper, wu:fj22d09 antikoerper, zgc:66387 antikoerper, Myst1 antikoerper, MOF antikoerper, MYST1 antikoerper, ZC2HC8 antikoerper, hMOF antikoerper, 2010203C02Rik antikoerper, 5830450F21Rik antikoerper, D7Ertd629e antikoerper, K(lysine) acetyltransferase 8 antikoerper, lysine acetyltransferase 8 antikoerper, kat8 antikoerper, KAT8 antikoerper, Kat8 antikoerper
- Hintergrund
-
Synonyms: Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ YBF2/SAS3 SAS2 and TIP60 protein 1, MYST-1, hMOF, KAT8, MOF, MYST1
Background: Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.
- Gen-ID
- 84148
- UniProt
- Q9H7Z6
-