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EIF5A Antikörper

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch EIF5A in WB, IHC, FACS, IHC (p) und IF (cc). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN6943242

Kurzübersicht für EIF5A Antikörper (ABIN6943242)

Target

Alle EIF5A Antikörper anzeigen
EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Reaktivität

  • 49
  • 27
  • 25
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 41
  • 6
  • 3
  • 1
Kaninchen

Klonalität

  • 36
  • 15
Monoklonal

Konjugat

  • 29
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser EIF5A Antikörper ist unkonjugiert

Applikation

  • 25
  • 16
  • 16
  • 14
  • 10
  • 9
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Klon

3A6
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    Recombinant protein within Human eIF5A between 50-150 amino acids

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

    Andere Bezeichnung

    eIF5A

    Hintergrund

    Synonyms: Eukaryotic translation initiation factor 5A-1, Eukaryotic initiation factor 5A isoform 1, Rev-binding factor, eIF-4D, eIF-5A-1, eIF-5A1, eIF-5A, EIF5A

    Background: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

    Gen-ID

    1984

    UniProt

    P63241

    Pathways

    Regulation of Muscle Cell Differentiation
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