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EEFSEC Antikörper (AA 21-120) (Biotin)

EEFSEC Reaktivität: Ratte ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN6943212
  • Target Alle EEFSEC Antikörper anzeigen
    EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))
    Bindungsspezifität
    • 14
    • 10
    • 8
    • 7
    • 1
    • 1
    AA 21-120
    Reaktivität
    • 22
    • 15
    • 9
    • 2
    • 1
    • 1
    Ratte
    Wirt
    • 36
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EEFSEC Antikörper ist konjugiert mit Biotin
    Applikation
    • 20
    • 15
    • 13
    • 13
    • 13
    • 6
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Dog,Cow,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EEFSEC
    Isotyp
    IgG
    Top Product
    Discover our top product EEFSEC Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))
    Andere Bezeichnung
    EEFSEC (EEFSEC Produkte)
    Synonyme
    RGD1560552 antikoerper, EFSEC antikoerper, SELB antikoerper, Selb antikoerper, sec antikoerper, eukaryotic elongation factor, selenocysteine-tRNA-specific antikoerper, eukaryotic elongation factor, selenocysteine-tRNA specific antikoerper, Eefsec antikoerper, EEFSEC antikoerper
    Hintergrund

    Synonyms: EFSEC, SELB_HUMAN_ Elongation factor for selenoprotein translation, Elongation factor sec, Eukaryotic elongation factor, selenocysteine tRNA specific, SELB, Selenocysteine specific elongation factor.

    Background: EEFSEC is a 596 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the GTP-binding elongation factor family. Functioning as a translation factor, SELB binds GTP and GDP and is necessary for the incorporation of selenocysteine into target proteins. The gene encoding SELB maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

    Gen-ID
    60678
    UniProt
    P57772
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