Dynamin 1-Like Antikörper (pSer616) (AbBy Fluor® 680)

Produktnummer ABIN6943125

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dynamin 1-Like in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Dynamin 1-Like Antikörper (pSer616) (AbBy Fluor® 680) (ABIN6943125)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Dynamin 1-Like Antikörper (AbBy Fluor® 680)

Bindungsspezifität: pSer616

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human DRP1 around the phosphorylation site of Ser616

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DRP1

Hintergrund:

Synonyms: DRP1 (phospho S616), p-DRP1 (phospho S616), P-DRP1 (Ser616), DLP1, dnm1l, DNM1L_HUMAN, Dnm1p/Vps1p-like protein, DVLP, Dymple, Dynamin 1 like, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin like protein, Dynamin related protein 1, Dynamin-1-like protein, Dynamin-like protein 4, Dynamin-like protein, Dynamin-like protein IV, Dynamin-related protein 1, DYNIV 11, FLJ41912, HdynIV, VPS1.

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Gen-ID: 10059

UniProt: O00429