DNASE1L2 Antikörper (AA 201-299)

Produktnummer ABIN6943057

Der Kaninchen Polyklonal Anti-DNASE1L2-Antikörper wurde für IF (cc), IF (p), ICC, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, DNASE1L2 in Proben von Ratte zu detektieren.

Kurzübersicht für DNASE1L2 Antikörper (AA 201-299) (ABIN6943057)

Target: DNASE1L2 (Deoxyribonuclease I-Like 2 (DNASE1L2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE1L2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DNASE1L2 Antikörper

Bindungsspezifität: AA 201-299

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNASE1L2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DNASE1L2

Target: DNASE1L2 (Deoxyribonuclease I-Like 2 (DNASE1L2))

Andere Bezeichnung: DNASE1L2

Hintergrund:

Synonyms: Deoxyribonuclease I-like 2, Deoxyribonuclease-1-like 2, DNase I homolog protein DHP1, DNase I-like 2, Dnase1l2, DNSL2_HUMAN.

Background: DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gen-ID: 1775

UniProt: Q92874