CHAF1A Antikörper (AA 100-300)
Kurzübersicht für CHAF1A Antikörper (AA 100-300) (ABIN6942547)
Target
Alle CHAF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 100-300
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Verwendungszweck
- CHAF1A (1D4) Monoclonal Antibody
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Kreuzreaktivität
- Human
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant protein within human p150 CAF1 aa 100-300.
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200), IP(1-2 μg)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
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Andere Bezeichnung
- CHAF1A
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Hintergrund
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Synonyms: Chromatin assembly factor 1 subunit A, Chromatin assembly factor I p150 subunit, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, hp150, p150 CAF1
Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
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Gen-ID
- 10036
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UniProt
- Q13111
Target
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