ADAP2 Antikörper (AA 201-300)

Produktnummer ABIN6942505

Der Kaninchen Polyklonal Anti-ADAP2-Antikörper wurde für WB, ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, ADAP2 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für ADAP2 Antikörper (AA 201-300) (ABIN6942505)

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ADAP2 Antikörper

Bindungsspezifität: AA 201-300

Spezifität: Possible cross-reactivity with ADAP1 (85 % homology with the immunogen sequence, 43 kDa)

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Centaurin alpha 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ADAP2

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Andere Bezeichnung: Centaurin alpha 2

Hintergrund:

Synonyms: ADAP2, ADAP2_HUMAN, Arf-GAP with dual PH domain-containing protein 2, ArfGAP with dual PH domains 2, cent b, Centa 2, CENTA2, Centaurin alpha 2, Centaurin alpha 2 protein, Centaurin beta, Centaurin-alpha-2, Cnt-a2, HSA272195.

Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1, Centaurin g3 and the recently discovered Centaurin a2. Expressed in a wide variety of tissues such as fat, heart and skeletal muscle, Centaurin a2 is thought to negatively regulate ARF-mediated actin rearrangement by binding activated PI 3-kinase. Although the exact function of Centaurin a2 is not yet known, its high sequence similarity with Centaurin a1 suggests that it may also act as an ARF6 GTPase.

Gen-ID: 55803

UniProt: Q9NPF8