Calsequestrin Antikörper (AA 100-250)

Produktnummer ABIN6942360

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Calsequestrin in IF (cc), FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Calsequestrin Antikörper (AA 100-250) (ABIN6942360)

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Calsequestrin Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 8G1

Produktdetails anti-Calsequestrin Antikörper

Bindungsspezifität: AA 100-250

Verwendungszweck: Calsequestrin-1 (8G1) Monoclonal Antibody

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human Calsequestrin 1 aa 100-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Calsequestrin

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Andere Bezeichnung: CASQ1

Hintergrund:

Synonyms: Calsequestrin 1, Calmitine, Calsequestrin skeletal muscle isoform, CASQ1, CASQ, PDIB1, VMCQA

Background: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

Gen-ID: 844

UniProt: P31415