BANF1 Antikörper

Produktnummer ABIN6942215

Der Kaninchen Monoklonal anti-BANF1 Antikörper (Klon 11H3) (ABIN6942215) detektiert spezifisch BANF1 in FACS, IF (cc), IF (p) und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für BANF1 Antikörper (ABIN6942215)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BANF1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 11H3

Produktdetails anti-BANF1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Full length recombinant protein of human BANF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Andere Bezeichnung: BANF1

Hintergrund:

Synonyms: Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor N-terminally processed, BANF1, BAF, BCRG1, NGPS, BCRP1,

Background: Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Gen-ID: 8815

UniProt: O75531