BANF1 Antikörper

Produktnummer ABIN6942215

Dieses Anti-BANF1-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von BANF1 in IF (cc), IF (p), IHC (p) und FACS. Geeignet für Human, Maus und Ratte.

Kurzübersicht für BANF1 Antikörper (ABIN6942215)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BANF1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 11H3

Produktdetails anti-BANF1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Full length recombinant protein of human BANF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Andere Bezeichnung: BANF1

Hintergrund:

Synonyms: Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor N-terminally processed, BANF1, BAF, BCRG1, NGPS, BCRP1,

Background: Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Gen-ID: 8815

UniProt: O75531